The Role of Hedgehog Signalling in the Formation of the Ventricular Septum

The Role of Hedgehog Signalling in the Formation of the Ventricular Septum

An incomplete septation of the ventricles in the vertebrate heart that disturbes the strict separation between the contents of the two ventricles is termed a ventricular septal defect (VSD). Together with bicuspid aortic valves, it is the most frequent congenital heart disease in humans. Until now,...

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Bibliographic Details
Main Authors:	Antonia Wiegering, Ulrich Rüther, Christoph Gerhardt
Format:	Article
Language:	English
Published:	MDPI AG 2017-12-01
Series:	Journal of Developmental Biology
Subjects:	ventricular septal defect VSD Smoothened SMO SAG purmorphamine oxysterols GSA-10 cilia Down syndrome
Online Access:	https://www.mdpi.com/2221-3759/5/4/17

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