Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core

Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core

Recent advances in G-quadruplex (GQ) studies have provided evidence for their important role in key biological processes (replication, transcription, genome stability, and epigenetics). These findings imply highly specific interactions between GQ structures and cellular proteins. The details of the...

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Bibliographic Details
Main Authors: Julia Svetlova, Makar Sardushkin, Natalia Kolganova, Edward Timofeev
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
G-quadruplex
recognition interface
thrombin binding aptamer
quadruplex core
loops
modification
Online Access:https://www.mdpi.com/2218-273X/11/9/1332

Internet

https://www.mdpi.com/2218-273X/11/9/1332

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