Conversion of adult human peripheral blood mononuclear cells into induced neural stem cell by using episomal vectors

Conversion of adult human peripheral blood mononuclear cells into induced neural stem cell by using episomal vectors

Human neural stem cells (NSCs) hold great promise for research and therapy in neural diseases. Many studies have shown direct induction of NSCs from human fibroblasts, which require an invasive skin biopsy and a prolonged period of expansion in cell culture prior to use. Peripheral blood (PB) is rou...

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Bibliographic Details
Main Authors: Xihe Tang, Shuyan Wang, Yunfei Bai, Jianyu Wu, Linlin Fu, Mo Li, Qunyuan Xu, Zhi-Qing David Xu, Y. Alex Zhang, Zhiguo Chen
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Stem Cell Research
Subjects:
Induced neural stem cells
Human peripheral blood mononuclear cells
Episomal vectors
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116000301

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