Pathogenesis and Therapeutic Mechanisms in  Immune Thrombocytopenia (ITP)

Pathogenesis and Therapeutic Mechanisms in  Immune Thrombocytopenia (ITP)

Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low  platelet counts. The pathogenesis of ITP remains unclear although both antibody‐mediated and/or  T cell‐mediated platelet destruction are key processes. In addition, impairment of T cells, cytokine  imbalances, and t...

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Bibliographic Details
Main Authors: Anne Zufferey, Rick Kapur, John W. Semple
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Journal of Clinical Medicine
Subjects:
immune thrombocytopenia (ITP)
 autoimmunity
 T cells
 B cells
 platelets
Online Access:http://www.mdpi.com/2077-0383/6/2/16

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