Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch

Abstract Background Tripterygium hypoglaucum Hutch (THH) both has prominent efficacy and unwarranted toxicity in the treatment of autoimmune diseases. Nevertheless, its pharmacological and toxicological profiles still remain to be elucidated. In the current study, the network pharmacology approach w...

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Bibliographic Details
Main Authors: Dan Zhang, Yizhu Dong, Jintao Lv, Bing Zhang, Xiaomeng Zhang, Zhijian Lin
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-021-03210-8