T Cell Calcium Signaling Regulation by the Co-Receptor CD5

T Cell Calcium Signaling Regulation by the Co-Receptor CD5

Calcium influx is critical for T cell effector function and fate. T cells are activated when T cell receptors (TCRs) engage peptides presented by antigen-presenting cells (APC), causing an increase of intracellular calcium (Ca2+) concentration. Co-receptors stabilize interactions between the TCR and...

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Bibliographic Details
Main Authors: Claudia M. Tellez Freitas, Deborah K. Johnson, K. Scott Weber
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
calcium signaling
T cell receptor (TCR)
co-receptors
CD-5
PD-1
CTL-4
Online Access:http://www.mdpi.com/1422-0067/19/5/1295

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