LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment
Mechanism of lymph node (LN) metastasis induced by tumor associated macrophages (TAMs) remains unclear. Here they demonstrate that a long noncoding RNA LNMAT1 promotes LN metastasis of bladder cancer via recruitment of TAMs through epigenetic regulation of CCL2 expression.
Bibliographic Details
Main Authors: |
Changhao Chen,
Wang He,
Jian Huang,
Bo Wang,
Hui Li,
Qingqing Cai,
Feng Su,
Junming Bi,
Hongwei Liu,
Bin Zhang,
Ning Jiang,
Guangzheng Zhong,
Yue Zhao,
Wen Dong,
Tianxin Lin |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2018-09-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-018-06152-x
|