Role of purinergic receptors in the activation of human airway smooth muscle cells by the antimicrobial peptide LL-37

Role of purinergic receptors in the activation of human airway smooth muscle cells by the antimicrobial peptide LL-37

Inflammatory cells that infiltrate and surround the airway smooth muscle (ASM) layer express antimicrobial peptides including the cathelicidin LL-37. LL-37 has been shown to activate epithelial cells by transactivation of the epidermal growth factor receptor (EGFR). Previously, we have shown that LL...

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Bibliographic Details
Main Authors: Suzanne Zuyderduyn, Dennis. K. Ninaber, Pieter. S. Hiemstra, Klaus. F. Rabe
Format: Article
Language:English
Published: European Respiratory Society 2006-12-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/cgi/content/full/15/101/182

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