Atherosclerosis and flow: roles of epigenetic modulation in vascular endothelium

Abstract Background Endothelial cell (EC) dysfunctions, including turnover enrichment, gap junction disruption, inflammation, and oxidation, play vital roles in the initiation of vascular disorders and atherosclerosis. Hemodynamic forces, i.e., atherprotective pulsatile (PS) and pro-atherogenic osci...

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Bibliographic Details
Main Authors: Ding-Yu Lee, Jeng-Jiann Chiu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-019-0551-8