Clinical Development of a Cytomegalovirus DNA Vaccine: From Product Concept to Pivotal Phase 3 Trial

Clinical Development of a Cytomegalovirus DNA Vaccine: From Product Concept to Pivotal Phase 3 Trial

2013 marks a milestone year for plasmid DNA vaccine development as a first-in-class cytomegalovirus (CMV) DNA vaccine enters pivotal phase 3 testing. This vaccine consists of two plasmids expressing CMV antigens glycoprotein B (gB) and phosphoprotein 65 (pp65) formulated with a CRL1005 poloxamer and...

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Bibliographic Details
Main Authors:	Michele Gerber, Alain P. Rolland, Jennifer A. Chaplin, Mary K. Wloch, Larry R. Smith
Format:	Article
Language:	English
Published:	MDPI AG 2013-09-01
Series:	Vaccines
Subjects:	plasmid DNA vaccine cytomegalovirus (CMV) glycoprotein B (gB) phosphoprotein 65 (pp65) poloxamer CRL1005 benzalkonium chloride (BAK) hematopoietic cell transplant (HCT) CMV end organ disease (EOD)
Online Access:	http://www.mdpi.com/2076-393X/1/4/398

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