Association of aescin with β- and γ-cyclodextrins studied by DFT calculations and spectroscopic methods

Association of aescin with β- and γ-cyclodextrins studied by DFT calculations and spectroscopic methods

Background: Aescin, a natural mixture of saponins occurring in Aesculus hippocastanum, exhibits important flebotonic properties, being used in the treatment of chronic venous insufficiency in legs. The inclusion of aescin into cyclodextrins (CDs) is a technical solution for its incorporation into th...

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Bibliographic Details
Main Authors: Ana I. Ramos, Pedro D. Vaz, Susana S. Braga, Artur M. S. Silva
Format: Article
Language:English
Published: Beilstein-Institut 2017-02-01
Series:Beilstein Journal of Nanotechnology
Subjects:
aescin
cyclodextrin inclusion
DFT
1H NMR
ROESY
Online Access:https://doi.org/10.3762/bjnano.8.37

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