The Neuroprotective Effects of SIRT1 on NMDA-Induced Excitotoxicity

Silent information regulator 1 (SIRT1), an NAD+-dependent deacetylase, is involved in the regulation of gene transcription, energy metabolism, and cellular aging and has become an important therapeutic target across a range of diseases. Recent research has demonstrated that SIRT1 possesses neuroprot...

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Bibliographic Details
Main Authors: Xiaorong Yang, Peipei Si, Huaping Qin, Litian Yin, Liang-Jun Yan, Ce Zhang
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/2823454