Sodium-glucose co-transporter 2 inhibition as a mitochondrial therapy for atrial fibrillation in patients with diabetes?

Abstract While patients with type 2 diabetes mellitus (T2DM) are at increased risk to develop atrial fibrillation (AF), the mechanistic link between T2DM and AF-susceptibility remains unclear. Common co-morbidities of T2DM, particularly hypertension, may drive AF in the setting of T2DM. But direct m...

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Bibliographic Details
Main Authors: Salva R. Yurista, Herman H. W. Silljé, Michiel Rienstra, Rudolf A. de Boer, B. Daan Westenbrink
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Cardiovascular Diabetology
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Online Access:https://doi.org/10.1186/s12933-019-0984-0

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