The relationship between mean platelet volume and mortality in patients in intensive care unit

• Main Authors: Mehmet Namuslu, Fırat Zafer Mengeloğlu, Fatih Demircan, Yaşar Altun
• Format: Article
• Language: English
• Published: Modestum Publishing LTD 2011-12-01
• Series: Journal of Clinical and Experimental Investigations
• Subjects: Intensive care unit; mortality; mean platelet volume
• Online Access: http://jceionline.org/upload/sayi/7/JCEI-00484.pdf
• ISSN: 1309-8578; 1309-6621

Objectives: In this study we aimed to investigate the mortality rate and the effect of mean platelet volume (MPV) which is a reliable parameter of Glascow Coma Scale (GCS) and thrombocyte function on the mortality of the patients in intensive care unit (ICU).Materials and methods: Data of consecutive 300 patients who interned in ICU were examined retrospectively and 119 patients of those were included in the study. GCS and MPV values, the mortality rate, length of stay in ICU and the mechanic ventilation duration of the patients were calculated. The level and volume of thrombocyte was measured by Beckman Coulter LH 780.Results: The most of our patients were interned from the emergency room (n:116). Fifty-one patiens were transferred to other departments and 19 patients were discharged. The number of the patients who died was 49 and the mortality rate was 41.2%. The mean GCS of survived patients (9.24±1.22) was significantly higher than the mean GCS of dead patients (6.78±1.76) (p<0.001). No statistically significant difference was found between the mean MPV values of the survived patients (8.87±1.34) and the dead patients (9.15±1.65) (p>0.05). Forty-four of 47 patients who had mechanic ventilation died.Conclusion: MPV values of the survived and dead patients were similar. GCS was found associated with mortality. This study supports that MPV values in admission to ICU don’t effect the mortality. J Clin Exp Invest 2011; 2 (4): 408-411