CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIA
Malaria and typhoid are known major causes of febrile conditions in the South-Eastern Nigeria, hence healthcare providers usually co-administer antibiotics and anti-malaria on febrile patients without or before proper laboratory diagnosis. Despite this, fever and other symptoms of malaria sometimes...
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Enugu State University of Science and Technology, ESUT, Enugu, Nigeria.
2017-01-01
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Series: | Journal of Experimental Research |
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doaj-f58a2bc74aea4186a437d57750ae67d72020-11-24T22:06:30ZengEnugu State University of Science and Technology, ESUT, Enugu, Nigeria.Journal of Experimental Research2315-96502502-05242017-01-01423159650CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIAMalaria and typhoid are known major causes of febrile conditions in the South-Eastern Nigeria, hence healthcare providers usually co-administer antibiotics and anti-malaria on febrile patients without or before proper laboratory diagnosis. Despite this, fever and other symptoms of malaria sometimes persist after repeated treatment regimens. We investigated possible co-existence and prevalence of another fever-causing condition and ndash; brucellosis, with malaria and typhoid. The systematic study done between January 2015 and June 2016 involved 682 febrile patients referred to a private medical laboratory in Enugu metropolis in South-Eastern Nigeria for investigation for malaria and typhoid only. The number was made up of 295(43.3%) males and 387(56.7%) females, aged between 10 and 50 years. Identification of malaria parasites was done using thick films stained with Giemsa stain while typhoid and brucellosis were investigated serologically using Chromatest and reg; febrile antigen kits. Our results showed prevalence of 39.1%, 66.0% and 28.6% for malaria, typhoid and brucellosis respectively in the studied population. Prevalence among male and female patients was 46.1% and 33.9% for malaria, 80.3% and 55.0% for typhoid, and 34.2% and 24.3% for brucellosis respectively. The results also showed that prevalence of malaria decreased with age while typhoid and brucellosis increased with age. We opine that 28.6% prevalence of brucellosis in a city with rare pastoral activities is high, and may be the cause of persistent fever after repeated combined treatment for malaria and typhoid. We advocate that these disease conditions should be simultaneously investigated for in all cases of febrile conditions to ensure wider investigation and treatment options, improvement on patients\' recovery time and reduction in man-hour loss.http://www.er-journal.com/papers/1483535735.pdf |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
title |
CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIA |
spellingShingle |
CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIA Journal of Experimental Research |
title_short |
CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIA |
title_full |
CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIA |
title_fullStr |
CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIA |
title_full_unstemmed |
CO-EXISTENCE AND SEROPREVALENCE OF BRUCELLOSIS IN A MALARIA-ENDEMIC METROPOLIS OF SOUTH-EASTERN NIGERIA |
title_sort |
co-existence and seroprevalence of brucellosis in a malaria-endemic metropolis of south-eastern nigeria |
publisher |
Enugu State University of Science and Technology, ESUT, Enugu, Nigeria. |
series |
Journal of Experimental Research |
issn |
2315-9650 2502-0524 |
publishDate |
2017-01-01 |
description |
Malaria and typhoid are known major causes of febrile conditions in the South-Eastern Nigeria, hence healthcare providers usually co-administer antibiotics and anti-malaria on febrile patients without or before proper laboratory diagnosis. Despite this, fever and other symptoms of malaria sometimes persist after repeated treatment regimens. We investigated possible co-existence and prevalence of another fever-causing condition and ndash; brucellosis, with malaria and typhoid. The systematic study done between January 2015 and June 2016 involved 682 febrile patients referred to a private medical laboratory in Enugu metropolis in South-Eastern Nigeria for investigation for malaria and typhoid only. The number was made up of 295(43.3%) males and 387(56.7%) females, aged between 10 and 50 years. Identification of malaria parasites was done using thick films stained with Giemsa stain while typhoid and brucellosis were investigated serologically using Chromatest and reg; febrile antigen kits. Our results showed prevalence of 39.1%, 66.0% and 28.6% for malaria, typhoid and brucellosis respectively in the studied population. Prevalence among male and female patients was 46.1% and 33.9% for malaria, 80.3% and 55.0% for typhoid, and 34.2% and 24.3% for brucellosis respectively. The results also showed that prevalence of malaria decreased with age while typhoid and brucellosis increased with age. We opine that 28.6% prevalence of brucellosis in a city with rare pastoral activities is high, and may be the cause of persistent fever after repeated combined treatment for malaria and typhoid. We advocate that these disease conditions should be simultaneously investigated for in all cases of febrile conditions to ensure wider investigation and treatment options, improvement on patients\' recovery time and reduction in man-hour loss. |
url |
http://www.er-journal.com/papers/1483535735.pdf |
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1725823417085591552 |