Recognition of unknown conserved alternatively spliced exons.

The split structure of most mammalian protein-coding genes allows for the potential to produce multiple different mRNA and protein isoforms from a single gene locus through the process of alternative splicing (AS). We propose a computational approach called UNCOVER based on a pair hidden Markov mode...

Full description

Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-07-01
Series:PLoS Computational Biology
Online Access:http://dx.doi.org/10.1371/journal.pcbi.0010015

Similar Items