Bisphenol A promotes stress granule assembly and modulates the integrated stress response

Bisphenol A promotes stress granule assembly and modulates the integrated stress response

Bisphenol-A (BPA) is a ubiquitous precursor of polycarbonate plastics that is found in the blood and serum of >92% of Americans. While BPA has been well documented to act as a weak estrogen receptor (ER) agonist, its effects on cellular stress are unclear. Here, we demonstrate that high-dose BPA...

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Bibliographic Details
Main Authors: Marta M. Fay, Daniella Columbo, Cecelia Cotter, Chandler Friend, Shawna Henry, Megan Hoppe, Paulina Karabelas, Corbyn Lamy, Miranda Lawell, Sarah Monteith, Christina Noyes, Paige Salerno, Jingyi Wu, Hedan Mindy Zhang, Paul J. Anderson, Nancy Kedersha, Pavel Ivanov, Natalie G. Farny
Format: Article
Language:English
Published: The Company of Biologists 2021-01-01
Series:Biology Open
Subjects:
bisphenol-a
integrated stress response
stress granules
translational control
Online Access:http://bio.biologists.org/content/10/1/bio057539

Internet

http://bio.biologists.org/content/10/1/bio057539

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