Primary Bone Marrow Mesenchymal Stromal Cells Rescue the Axonal Phenotype of Twitcher Mice

Primary Bone Marrow Mesenchymal Stromal Cells Rescue the Axonal Phenotype of Twitcher Mice

Krabbe's disease (KD) is a demyelinating disorder caused by the deficiency of lysosomal galactocerebrosi-dase (GALC), affecting both the central (CNS) and the peripheral nervous system (PNS). A current therapy, hematopoietic stem cell transplantation (HSCT), is ineffective at correcting the PNS...

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Main Authors: Catarina Oliveira Miranda, Carla Andreia Teixeira, Vera Filipe Sousa, Telma Emanuela Santos, Márcia Almeida Liz, Ana Maio Marques, Perpétua Pinto-Do-Ó, Mónica Mendes Sousa
Format: Article
Language:English
Published: SAGE Publishing 2014-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368913X669752

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