Radioiodine Therapy in Differentiated Thyroid Cancer: The First Targeted Therapy in Oncology

Iodide uptake across the membranes of thyroid follicular cells and cancer cells occurs through an active transport process mediated by the sodium-iodide symporter (NIS). The rat and human NIS-coding genes were cloned and identified in 1996. Evaluation of NIS gene and protein expression is critical f...

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Bibliographic Details
Main Authors: June-Key Chung, Gi Jeong Cheon
Format: Article
Language:English
Published: Academya Publishing Co. 2014-09-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-233.pdf