Attenuating Diabetic Vascular and Neuronal Defects by Targeting P2rx7

Attenuating Diabetic Vascular and Neuronal Defects by Targeting P2rx7

Retinal vascular and neuronal degeneration are established pathological features of diabetic retinopathy. Data suggest that defects in the neuroglial network precede the clinically recognisable vascular lesions in the retina. Therefore, new treatments that target early-onset neurodegeneration would...

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Bibliographic Details
Main Authors: Sofia Pavlou, Josy Augustine, Rónán Cunning, Kevin Harkin, Alan W. Stitt, Heping Xu, Mei Chen
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic retinopathy
P2rx7
3TC
retinal function
Online Access:https://www.mdpi.com/1422-0067/20/9/2101

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