Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)

BACKGROUND This work describes a chemical study of the essential oil from leaves of Xylopia ochrantha, an endemic Annonaceae species from Brazil, and its activity against Biomphalaria species. Considering its poor solubility in aqueous medium, the essential oil was nanoemulsified to evaluate its ac...

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Main Authors: Fernanda de Paula Araújo, Ricardo Diego Duarte Galhardo de Albuquerque, Leonardo da Silva Rangel, Gabriel Rocha Caldas, Luís Armando Cândido Tietbohl, Marcelo Guerra Santos, Eduardo Ricci-Júnior, Silvana Thiengo, Monica Ammon Fernandez, José Augusto Albuquerque dos Santos, Robson Xavier Faria, Leandro Rocha
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2019-04-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100318&lng=en&tlng=en
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spelling doaj-f5672bc08ecf4348870c3855145701ab2020-11-25T02:09:25ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.1678-80602019-04-01114010.1590/0074-02760180489S0074-02762019000100318Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)Fernanda de Paula AraújoRicardo Diego Duarte Galhardo de AlbuquerqueLeonardo da Silva RangelGabriel Rocha CaldasLuís Armando Cândido TietbohlMarcelo Guerra SantosEduardo Ricci-JúniorSilvana ThiengoMonica Ammon FernandezJosé Augusto Albuquerque dos SantosRobson Xavier FariaLeandro RochaBACKGROUND This work describes a chemical study of the essential oil from leaves of Xylopia ochrantha, an endemic Annonaceae species from Brazil, and its activity against Biomphalaria species. Considering its poor solubility in aqueous medium, the essential oil was nanoemulsified to evaluate its action on controlling some mollusc species of genus Biomphalaria, snail hosts of Schistosoma mansoni that causes schistosomiasis, which mainly affects tropical and subtropical countries. OBJECTIVES The main aims of this work were to analyse the chemical composition of essential oil from X. ochrantha, and to evaluate the effect of its nanoemulsion on molluscs of genus Biomphalaria and their oviposition. METHODS Chemical analysis was performed by gas chromatography coupled to mass spectrometry. Nanoemulsions were prepared by a low energy method and characterised by particle size and polydispersity index. Biological assays evaluating the mortality of adult species of B. glabrata, B. straminea and B. tenagophila and their ovipositions upon contact with the most stable nanoemulsion during 24 and 48 h were performed. FINDINGS Chemical analysis by mass spectrometry revealed the majority presence of bicyclogermacrene and germacrene D in the essential oil. The formulation with a hydrophilic-lipophilic balance (HLB) of 9.26 was the most suitable for the oil delivery system. This nanoemulsion caused the mortality in B. tenagophila, B. straminea and B. glabarata of different sizes at levels ranging from 50 to 100% in 48 h. Additionally, the formulation could inhibit the development of deposited eggs. CONCLUSION Thus, these results suggest the use of nanoemulsified essential oil from X. ochrantha as a possible alternative in controlling some Biomphalaria species involved in the schistosomiasis cycle.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100318&lng=en&tlng=enessential oil nanoemulsionXylopia ochranthamollusc controlBiomphalariaschistosomiasis
collection DOAJ
language English
format Article
sources DOAJ
author Fernanda de Paula Araújo
Ricardo Diego Duarte Galhardo de Albuquerque
Leonardo da Silva Rangel
Gabriel Rocha Caldas
Luís Armando Cândido Tietbohl
Marcelo Guerra Santos
Eduardo Ricci-Júnior
Silvana Thiengo
Monica Ammon Fernandez
José Augusto Albuquerque dos Santos
Robson Xavier Faria
Leandro Rocha
spellingShingle Fernanda de Paula Araújo
Ricardo Diego Duarte Galhardo de Albuquerque
Leonardo da Silva Rangel
Gabriel Rocha Caldas
Luís Armando Cândido Tietbohl
Marcelo Guerra Santos
Eduardo Ricci-Júnior
Silvana Thiengo
Monica Ammon Fernandez
José Augusto Albuquerque dos Santos
Robson Xavier Faria
Leandro Rocha
Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
Memórias do Instituto Oswaldo Cruz.
essential oil nanoemulsion
Xylopia ochrantha
mollusc control
Biomphalaria
schistosomiasis
author_facet Fernanda de Paula Araújo
Ricardo Diego Duarte Galhardo de Albuquerque
Leonardo da Silva Rangel
Gabriel Rocha Caldas
Luís Armando Cândido Tietbohl
Marcelo Guerra Santos
Eduardo Ricci-Júnior
Silvana Thiengo
Monica Ammon Fernandez
José Augusto Albuquerque dos Santos
Robson Xavier Faria
Leandro Rocha
author_sort Fernanda de Paula Araújo
title Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
title_short Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
title_full Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
title_fullStr Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
title_full_unstemmed Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
title_sort nanoemulsion containing essential oil from xylopia ochrantha mart. produces molluscicidal effects against different species of biomphalaria (schistosoma hosts)
publisher Instituto Oswaldo Cruz, Ministério da Saúde
series Memórias do Instituto Oswaldo Cruz.
issn 1678-8060
publishDate 2019-04-01
description BACKGROUND This work describes a chemical study of the essential oil from leaves of Xylopia ochrantha, an endemic Annonaceae species from Brazil, and its activity against Biomphalaria species. Considering its poor solubility in aqueous medium, the essential oil was nanoemulsified to evaluate its action on controlling some mollusc species of genus Biomphalaria, snail hosts of Schistosoma mansoni that causes schistosomiasis, which mainly affects tropical and subtropical countries. OBJECTIVES The main aims of this work were to analyse the chemical composition of essential oil from X. ochrantha, and to evaluate the effect of its nanoemulsion on molluscs of genus Biomphalaria and their oviposition. METHODS Chemical analysis was performed by gas chromatography coupled to mass spectrometry. Nanoemulsions were prepared by a low energy method and characterised by particle size and polydispersity index. Biological assays evaluating the mortality of adult species of B. glabrata, B. straminea and B. tenagophila and their ovipositions upon contact with the most stable nanoemulsion during 24 and 48 h were performed. FINDINGS Chemical analysis by mass spectrometry revealed the majority presence of bicyclogermacrene and germacrene D in the essential oil. The formulation with a hydrophilic-lipophilic balance (HLB) of 9.26 was the most suitable for the oil delivery system. This nanoemulsion caused the mortality in B. tenagophila, B. straminea and B. glabarata of different sizes at levels ranging from 50 to 100% in 48 h. Additionally, the formulation could inhibit the development of deposited eggs. CONCLUSION Thus, these results suggest the use of nanoemulsified essential oil from X. ochrantha as a possible alternative in controlling some Biomphalaria species involved in the schistosomiasis cycle.
topic essential oil nanoemulsion
Xylopia ochrantha
mollusc control
Biomphalaria
schistosomiasis
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100318&lng=en&tlng=en
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