Aquaporins: More Than Functional Monomers in a Tetrameric Arrangement

Aquaporins: More Than Functional Monomers in a Tetrameric Arrangement

Aquaporins (AQPs) function as tetrameric structures in which each monomer has its own permeable pathway. The combination of structural biology, molecular dynamics simulations, and experimental approaches has contributed to improve our knowledge of how protein conformational changes can challenge its...

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Bibliographic Details
Main Authors: Marcelo Ozu, Luciano Galizia, Cynthia Acuña, Gabriela Amodeo
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
water channel
osmotic permeability
gating
cooperative mechanism
Online Access:https://www.mdpi.com/2073-4409/7/11/209

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