Bilirubin Protects Transplanted Islets by Targeting Ferroptosis

Islet transplantation is an attractive treatment for type 1 diabetic patients. However, transplanted islets suffered from considerable cell death due to inflammatory reactions and oxidative stress. Ferroptosis is a programmed death characterized by iron-dependent lipid peroxidation, which has been i...

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Bibliographic Details
Main Authors: Qing Yao, Rui Sun, Shihui Bao, Ruijie Chen, Longfa Kou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00907/full