A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns

A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns

Abstract Background Epigenetic modifications, including CG methylation (a major form of DNA methylation) and histone modifications, interact with each other to shape their genomic distribution patterns. However, the entire picture of the epigenetic crosstalk regulating the CG methylation pattern is...

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Bibliographic Details
Main Authors: Wan Kin Au Yeung, Osamu Maruyama, Hiroyuki Sasaki
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Bioinformatics
Subjects:
DNA methylation
Histone modification
Epigenetic crosstalk
Convolutional neural network
Oocyte
Stem cell
Online Access:https://doi.org/10.1186/s12859-021-04272-8

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