A distinct transcriptional signature of antidepressant response in hippocampal dentate gyrus granule cells
Abstract Major depressive disorder is the most prevalent mental illness worldwide, still its pharmacological treatment is limited by various challenges, such as the large heterogeneity in treatment response and the lack of insight into the neurobiological pathways underlying this phenomenon. To deco...
Main Authors: | David P. Herzog, Diego Pascual Cuadrado, Giulia Treccani, Tanja Jene, Verena Opitz, Annika Hasch, Beat Lutz, Klaus Lieb, Inge Sillaber, Michael A. van der Kooij, Vijay K. Tiwari, Marianne B. Müller |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
|
Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-020-01136-2 |
Similar Items
-
Facilitating Granule Cell Survival and Maturation in Dentate Gyrus With Baicalin for Antidepressant Therapeutics
by: Fan Zhao, et al.
Published: (2020-09-01) -
Effects of antidepressants on the ventral dentate gyrus
by: Carazo Arias, Elena
Published: (2021) -
Dentate gyrus activin signaling mediates the antidepressant response
by: Mark M. Gergues, et al.
Published: (2021-01-01) -
Cell-Biological Requirements for the Generation of Dentate Gyrus Granule Neurons
by: Maryam Hatami, et al.
Published: (2018-11-01) -
The Functional Integration of Adult-born Granule Cells into Dentate Gyrus Circuitry
by: Krakowski, Aneta
Published: (2010)