Is it always unethical to use a placebo in a clinical trial?

BACKGROUND TO THE DEBATE: Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a...

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Main Authors: Andreas Stang, Hans-Werner Hense, Karl-Heinz Jöckel, Erick H Turner, Martin R Tramèr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-03-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1069666?pdf=render
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spelling doaj-f54ef04b58544686819b61097fe5ce8f2020-11-24T21:48:32ZengPublic Library of Science (PLoS)PLoS Medicine1549-12771549-16762005-03-0123e7210.1371/journal.pmed.0020072Is it always unethical to use a placebo in a clinical trial?Andreas StangHans-Werner HenseKarl-Heinz JöckelErick H TurnerMartin R TramèrBACKGROUND TO THE DEBATE: Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a placebo should not be used. But proponents argue that placebo trials are still crucial to prove the efficacy and safety of many treatments.http://europepmc.org/articles/PMC1069666?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Andreas Stang
Hans-Werner Hense
Karl-Heinz Jöckel
Erick H Turner
Martin R Tramèr
spellingShingle Andreas Stang
Hans-Werner Hense
Karl-Heinz Jöckel
Erick H Turner
Martin R Tramèr
Is it always unethical to use a placebo in a clinical trial?
PLoS Medicine
author_facet Andreas Stang
Hans-Werner Hense
Karl-Heinz Jöckel
Erick H Turner
Martin R Tramèr
author_sort Andreas Stang
title Is it always unethical to use a placebo in a clinical trial?
title_short Is it always unethical to use a placebo in a clinical trial?
title_full Is it always unethical to use a placebo in a clinical trial?
title_fullStr Is it always unethical to use a placebo in a clinical trial?
title_full_unstemmed Is it always unethical to use a placebo in a clinical trial?
title_sort is it always unethical to use a placebo in a clinical trial?
publisher Public Library of Science (PLoS)
series PLoS Medicine
issn 1549-1277
1549-1676
publishDate 2005-03-01
description BACKGROUND TO THE DEBATE: Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a placebo should not be used. But proponents argue that placebo trials are still crucial to prove the efficacy and safety of many treatments.
url http://europepmc.org/articles/PMC1069666?pdf=render
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