Is it always unethical to use a placebo in a clinical trial?
BACKGROUND TO THE DEBATE: Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a...
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2005-03-01
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doaj-f54ef04b58544686819b61097fe5ce8f2020-11-24T21:48:32ZengPublic Library of Science (PLoS)PLoS Medicine1549-12771549-16762005-03-0123e7210.1371/journal.pmed.0020072Is it always unethical to use a placebo in a clinical trial?Andreas StangHans-Werner HenseKarl-Heinz JöckelErick H TurnerMartin R TramèrBACKGROUND TO THE DEBATE: Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a placebo should not be used. But proponents argue that placebo trials are still crucial to prove the efficacy and safety of many treatments.http://europepmc.org/articles/PMC1069666?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andreas Stang Hans-Werner Hense Karl-Heinz Jöckel Erick H Turner Martin R Tramèr |
spellingShingle |
Andreas Stang Hans-Werner Hense Karl-Heinz Jöckel Erick H Turner Martin R Tramèr Is it always unethical to use a placebo in a clinical trial? PLoS Medicine |
author_facet |
Andreas Stang Hans-Werner Hense Karl-Heinz Jöckel Erick H Turner Martin R Tramèr |
author_sort |
Andreas Stang |
title |
Is it always unethical to use a placebo in a clinical trial? |
title_short |
Is it always unethical to use a placebo in a clinical trial? |
title_full |
Is it always unethical to use a placebo in a clinical trial? |
title_fullStr |
Is it always unethical to use a placebo in a clinical trial? |
title_full_unstemmed |
Is it always unethical to use a placebo in a clinical trial? |
title_sort |
is it always unethical to use a placebo in a clinical trial? |
publisher |
Public Library of Science (PLoS) |
series |
PLoS Medicine |
issn |
1549-1277 1549-1676 |
publishDate |
2005-03-01 |
description |
BACKGROUND TO THE DEBATE: Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a placebo should not be used. But proponents argue that placebo trials are still crucial to prove the efficacy and safety of many treatments. |
url |
http://europepmc.org/articles/PMC1069666?pdf=render |
work_keys_str_mv |
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