Genetically engineered synthetic miniaturized versions of Plasmodium falciparum UvrD helicase are catalytically active.

Helicases catalyze unwinding of double stranded nucleic acids in an energy-dependent manner. We have reported characterization of UvrD helicase from Plasmodium falciparum. We reported that the N-terminal and C-terminal fragments of PfUvrD contain characteristic ATPase and DNA helicase activities. He...

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Bibliographic Details
Main Authors: Abulaish Ansari, Mohammed Tarique, Renu Tuteja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946578?pdf=render