Acute macular neuroretinopathy (AMN) following COVID-19 vaccination

Acute macular neuroretinopathy (AMN) following COVID-19 vaccination

Purpose: To describe a case of acute macular neuroretinopathy (AMN) in a 23-year-old Caucasian female after a COVID-19 vaccination (Vaxzevira). Observations: Our patient perceived visual symptoms in both eyes one day after COVID-19 vaccination. Hyporeflective petalloid shaped perifoveal lesions appe...

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Bibliographic Details
Main Authors: Daniela Drüke, Uwe Pleyer, Hans Hoerauf, Nicolas Feltgen, Sebastian Bemme
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
AMN
COVID-19 vaccine vaxzevria
EZ disruption
IZ disruption
Paracentral scotomas
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993621002164
Description
Summary:Purpose: To describe a case of acute macular neuroretinopathy (AMN) in a 23-year-old Caucasian female after a COVID-19 vaccination (Vaxzevira). Observations: Our patient perceived visual symptoms in both eyes one day after COVID-19 vaccination. Hyporeflective petalloid shaped perifoveal lesions appeared in infrared reflectance (IR) imaging, and Spectral domain-optical coherence tomography (SD-OCT) revealed structural alterations of outer retinal layers that resulted in persistent disruption of the ellipsoid zone (EZ) and the interdigitation zone (IZ). Conclusions and importance: We report a novel association between AMN and COVID-19 vaccination. In addition to a febrile infection and oral contraception, previous vaccination should also be considered a potential risk factor for AMN.
ISSN:2451-9936

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