Phage-like Streptococcus pyogenes chromosomal islands (SpyCI) and mutator phenotypes: control by growth state and rescue by a SpyCI-encoded promoter

Phage-like Streptococcus pyogenes chromosomal islands (SpyCI) and mutator phenotypes: control by growth state and rescue by a SpyCI-encoded promoter

We recently showed that a prophage-like Streptococcus pyogenes chromosomal island (SpyCI) controls DNA mismatch repair (MMR) and other repair functions in M1 genome strain SF370 by dynamic excision and reintegration into the 5’ end of mutL in response to growth, causing the cell to alternate between...

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Bibliographic Details
Main Authors: Julie eScott, Scott Van Nguyen, Catherine eKing, Christina G. Hendrickson, William Michael Mcshan
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Microbiology
Subjects:
DNA Mismatch Repair
Prophages
Streptococcus pyogenes
chromosomal islands
SpyCI
mutator phenotype
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00317/full

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