Design and Synthesis of a Compound Library Exploiting 5-Methoxyleoligin as Potential Cholesterol Efflux Promoter

Design and Synthesis of a Compound Library Exploiting 5-Methoxyleoligin as Potential Cholesterol Efflux Promoter

5-Methoxyleoligin and leoligin are natural occurring lignans derived from Edelweiss (<i>Leontopodium nivale</i> ssp. <i>alpinum</i>), displaying potent pro-angiogenic and pro-arteriogenic activity. Cholesterol efflux from macrophages is associated with reverse cholesterol tra...

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Bibliographic Details
Main Authors: Thomas Linder, Sophie Geyrhofer, Eleni Papaplioura, Limei Wang, Atanas G. Atanasov, Hermann Stuppner, Verena M. Dirsch, Michael Schnürch, Marko D. Mihovilovic
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
natural product synthesis
cardiovascular diseases
lignans
macrophage cholesterol efflux
Online Access:https://www.mdpi.com/1420-3049/25/3/662

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https://www.mdpi.com/1420-3049/25/3/662

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