Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death.

Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death.

We have previously investigated the physiological role of C-type natriuretic peptide (CNP) on endochondral bone growth, mainly with mutant mouse models deficient in CNP, and reported that CNP is indispensable for physiological endochondral bone growth in mice. However, the survival rate of CNP knock...

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Bibliographic Details
Main Authors: Toshihito Fujii, Keisho Hirota, Akihiro Yasoda, Akiko Takizawa, Naomi Morozumi, Ryuichi Nakamura, Takafumi Yotsumoto, Eri Kondo, Yui Yamashita, Yoriko Sakane, Yugo Kanai, Yohei Ueda, Ichiro Yamauchi, Shigeki Yamanaka, Kazumasa Nakao, Koichiro Kuwahara, Toshimasa Jindo, Mayumi Furuya, Tomoji Mashimo, Nobuya Inagaki, Tadao Serikawa, Kazuwa Nakao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5864047?pdf=render

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http://europepmc.org/articles/PMC5864047?pdf=render

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