Prevalence and Molecular Characterization of Defective DNA Mismatch Repair in Small-bowel Carcinoma in a Japanese Hospital-based Population

Prevalence and Molecular Characterization of Defective DNA Mismatch Repair in Small-bowel Carcinoma in a Japanese Hospital-based Population

Objectives: To investigate the prevalence and molecular characteristics of defective DNA mismatch repair (dMMR) in small-bowel carcinoma (SBC) in a Japanese-hospital population. Methods: Immunohistochemistry was performed to evaluate the expression of MMR proteins (MLH1, MSH2, MSH6, and PMS2) in for...

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Bibliographic Details
Main Authors: Tetsuya Ito, Hideyuki Ishida, Okihide Suzuki, Noriyasu Chika, Kunihiko Amano, Keiichiro Ishibashi, Nao Kamae, Yuhki Tada, Kiwamu Akagi, Hidetaka Eguchi, Yasushi Okazaki
Format: Article
Language:English
Published: The Japan Society of Coloproctology 2020-10-01
Series:Journal of the Anus, Rectum and Colon
Subjects:
small-bowel carcinoma
dna mismatch repair
lynch syndrome
microsatellite instability
universal tumor screening
Online Access:https://www.jstage.jst.go.jp/article/jarc/4/4/4_2020-026/_pdf/-char/en

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