GATA6 Exerts Potent Lung Cancer Suppressive Function by Inducing Cell Senescence

GATA6 Exerts Potent Lung Cancer Suppressive Function by Inducing Cell Senescence

Lung cancer is the leading cause of cancer-related deaths worldwide. Tumor suppressor genes (TSGs) play a critical role in restricting tumorigenesis and impact the therapeutic effect of various treatments. However, TSGs remain to be systemically determined in lung cancer. Here, we identified GATA6 a...

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Bibliographic Details
Main Authors: Wensheng Chen, Zhipeng Chen, Miaomiao Zhang, Yahui Tian, Lu Liu, Ruirui Lan, Guandi Zeng, Xiaolong Fu, Guoqing Ru, Wanting Liu, Liang Chen, Zhenzhen Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
lung cancer
tumor suppressor genes
GATA6
p21
AKT
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00824/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00824/full

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