Long-Term Single-Dose Efficacy of a Vesicular Stomatitis Virus-Based Andes Virus Vaccine in Syrian Hamsters

Long-Term Single-Dose Efficacy of a Vesicular Stomatitis Virus-Based Andes Virus Vaccine in Syrian Hamsters

Andes virus (ANDV) is highly pathogenic in humans and is the primary etiologic agent of hantavirus cardiopulmonary syndrome (HCPS) in South America. Case-fatality rates are as high as 50% and there are no approved vaccines or specific therapies for infection. Our laboratory has recently developed a...

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Bibliographic Details
Main Authors: Joseph Prescott, Blair L. DeBuysscher, Kyle S. Brown, Heinz Feldmann
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Viruses
Subjects:
Andes virus
vaccine
durability
antibody response
hantavirus
Online Access:http://www.mdpi.com/1999-4915/6/2/516

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