Role of Fluid Milk in Attenuating Postprandial Hyperglycemia and Hypertriglyceridemia

• Main Authors: Miriam Leary, Hirofumi Tanaka
• Format: Article
• Language: English
• Published: MDPI AG 2020-12-01
• Series: Nutrients
• Subjects: milk; dairy; postprandial metabolism; hyperglycemia; hypertriglyceridemia
• Online Access: https://www.mdpi.com/2072-6643/12/12/3806

Postprandial plasma glucose and triglyceride concentrations are predictive of relative cardiovascular disease (CVD) risk, and the pathogenesis of both insulin resistance and atherosclerosis has been attributed to acute states of hyperglycemia and hypertriglyceridemia. Postprandial lipemia and hyperglycemia suppress vascular reactivity and induce endothelial dysfunction. Epidemiological studies suggest that chronically-high consumption of milk and milk products is associated with a reduced risk of type 2 diabetes, metabolic syndrome, and CVD. The addition of dairy products to meals high in carbohydrates and fat may lessen these risks through reductions in postprandial glucose and triglyceride responses. Purported mechanisms include dairy proteins and bioactive compounds, which may explain the inverse relationship between dairy consumption and cardiometabolic diseases. The current review evaluates the available literature describing the relationships between metabolic dysfunction, postprandial metabolism, and vascular dysfunction and discusses the potential role of milk and dairy products in attenuating these impairments.