Studies on the substrate specificity and inhibition of prostaglandin biosynthesis with methyl branched isomers of eicosa-8, 11, 14-trienoic acid

Seven radioactive methyl branched isomers of eicosa-8, 11, 14-trienoic acid, in which a methyl branch was located at carbon 2, 5, 10, 13, 17, 18, or 19, were used as substrates to study their enzymatic conversion into homologues of prostaglandin E1 by microsomes from bovine vesicular glands. The pro...

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Bibliographic Details
Main Authors: U H Do, H Sprecher
Format: Article
Language:English
Published: Elsevier 1976-07-01
Series:Journal of Lipid Research
Subjects:
I50
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349294