Smoking, DNA Methylation, and Breast Cancer: A Mendelian Randomization Study

Smoking, DNA Methylation, and Breast Cancer: A Mendelian Randomization Study

BackgroundSmoking was strongly associated with breast cancer in previous studies. Whether smoking promotes breast cancer through DNA methylation remains unknown.MethodsTwo-sample Mendelian randomization (MR) analyses were conducted to assess the causal effect of smoking-related DNA methylation on br...

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Bibliographic Details
Main Authors: Haibo Tang, Desong Yang, Chaofei Han, Ping Mu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
Mendelian randomization (MR)
smoking
DNA methylation
breast cancer
causal inference
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.745918/full

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