Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice.

Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice.

Airway surface dehydration, caused by an imbalance between secretion and absorption of ions and fluid across the epithelium and/or increased epithelial mucin secretion, impairs mucociliary clearance. Recent evidence suggests that this mechanism may be implicated in chronic obstructive pulmonary dise...

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Bibliographic Details
Main Authors: Leen J M Seys, Fien M Verhamme, Lisa L Dupont, Elke Desauter, Julia Duerr, Ayca Seyhan Agircan, Griet Conickx, Guy F Joos, Guy G Brusselle, Marcus A Mall, Ken R Bracke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466573?pdf=render

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