Preparation and Characterization of Silk Fibroin Nanoparticles as a Potential Drug Delivery System for 5-Fluorouracil

Preparation and Characterization of Silk Fibroin Nanoparticles as a Potential Drug Delivery System for 5-Fluorouracil

Purpose: The aim of this study is to prepare 5-fluorouracil (5-FU) loaded silk fibroin nanoparticles (SFNPs) and to achieve a controlled release delivery system with the high loading capacity. Methods: SFNPs with 1:1, 1:3, and 1:10 ratios of 5-FU to silk fibroin were prepared. SFNPs were characteriz...

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Bibliographic Details
Main Authors: Hamid Rahmani, Ali Fattahi, Komail Sadrjavadi, Salar Khaledian, Yalda Shokoohinia
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-10-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
sf
5-fluorouracile
nanoparticle
precipitation
cytotoxicity
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-27494

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