Current Views on the Interplay between Tyrosine Kinases and Phosphatases in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a myeloproliferative disorder characterized by BCR-ABL1 oncogene expression. This dysregulated protein-tyrosine kinase (PTK) is known as the principal driver of the disease and is targeted by tyrosine kinase inhibitors (TKIs). Extensive documentation has elucidated...

Full description

Bibliographic Details
Main Authors: Christian Boni, Claudio Sorio
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
CML
Online Access:https://www.mdpi.com/2072-6694/13/10/2311