On the use of algebraic topology concepts to check the consistency of genome assembly

This paper presents a preliminary work consisting of two contributions. The first one is the design of a very efficient algorithm based on an “Overlap-Layout-Consensus” (OLC) graph to assemble the long reads provided by 3rd generation technologies. The second concerns the analysis of this graph usin...

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Bibliographic Details
Main Author: Jean-François Gibrat
Format: Article
Language:English
Published: The Biophysical Society of Japan 2019-11-01
Series:Biophysics and Physicobiology
Subjects:
Online Access:https://doi.org/10.2142/biophysico.16.0_444