Dimethyl fumarate modulates antioxidant and lipid metabolism in oligodendrocytes

Oxidative stress contributes to pathology associated with inflammatory brain disorders and therapies that upregulate antioxidant pathways may be neuroprotective in diseases such as multiple sclerosis. Dimethyl fumarate, a small molecule therapeutic for multiple sclerosis, activates cellular antioxid...

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Bibliographic Details
Main Authors: He Huang, Alexandra Taraboletti, Leah P. Shriver
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231715000427