the evaluation the efficiency of Proteflazidum in complex treatment of herpetic uveitis

• Main Authors: H. M. Kamilov, M. N. Yuldosheva, M. S. Kasimova
• Format: Article
• Language: Russian
• Published: Ophthalmology Publishing Group 2014-07-01
• Series: Oftalʹmologiâ
• Subjects: herpetic uveitis; drug Proteflazidum; complex treatment
• Online Access: http://www.ophthalmojournal.com/index.php/opht/article/view/141

<p><strong>Purpose</strong>: to determine efficiency of Proteflazidum in treatment of herpetic uveitis.<br /><strong>Methods</strong>: 87 eyes of 78 patients, suffering by different forms herpetic uveitis were studied. In I (control) group (41 eyes) applied traditional treatment. In II (basic) group (46 eyes) as a part of complex therapy applied Proteflazid inside. Carrying out Immunoenzyme analysis of blood and polymerase chain reaction studies with conjunctival scrapings in dynamics of treatment herpetic cornea inflam- mation, has been allowed to estimate objectively efficiency of spent therapy and degree cure of patients.<br /><strong>Results</strong>: the combined treatment by a preparation of Proteflazidum and Ganciclovir for eye herpetic infection promotes stabiliza- tion of infectious process at early stages with preservation and improvement of visual functions (93.5%), to lengthening of the periods of remission (957%), normalization laboratory given (97.6%) and immunological indicators (94.9%). Data of IFA, PCR and immunogram blood in the treatment of herpetic uveitis can objectively evaluate the effectiveness of the therapy and the degree of cure of patients.<br /><strong>Conclusion</strong>: Сomplex treatment of herpetic uveitis with drug Proteflazidum is more effective than traditional treatment regimen.</p>