Estrogen receptor hormone agonists limit trauma hemorrhage shock-induced gut and lung injury in rats.

Estrogen receptor hormone agonists limit trauma hemorrhage shock-induced gut and lung injury in rats.

Acute lung injury (ALI) and the development of the multiple organ dysfunction syndrome (MODS) is a major cause of death in trauma patients. Earlier studies in trauma hemorrhagic shock (T/HS) have documented that splanchnic ischemia leading to gut inflammation and loss of barrier function is an initi...

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Bibliographic Details
Main Authors: Danielle Doucet, Chirag Badami, David Palange, R Paul Bonitz, Qi Lu, Da-Zhong Xu, Kolenkode B Kannan, Iriana Colorado, Rena Feinman, Edwin A Deitch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2828476?pdf=render

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