AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity

AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity

In this study, we demonstrate that activation of AMP-activated protein kinase (AMPK) with glabridin alleviates adiposity and hyperlipidemia in obesity. In several obese rodent models, glabridin decreased body weight and adiposity with a concomitant reduction in fat cell size. Further, glabridin amel...

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Bibliographic Details
Main Authors: Joo-Won Lee, Sung Sik Choe, Hagoon Jang, Jiyeong Kim, Hyun Woo Jeong, Hyunsun Jo, Kyeong-Hoon Jeong, Surendar Tadi, Myoung Gyu Park, Tae Hwan Kwak, Jin Man Kim, Dong-Hoon Hyun, Jae Bum Kim
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Journal of Lipid Research
Subjects:
AMP-activated protein kinase
fatty acid oxidation
fatty liver
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345041

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