Research progress in the application of OCTA technology in primary glaucoma

• Main Authors: Xiang-Xiang Yang, Yuan He, Jian Zhang
• Format: Article
• Language: English
• Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-01-01
• Series: Guoji Yanke Zazhi
• Subjects: optical coherence tomography angiography; primary open angle glaucoma; primary angle-closure glaucoma; vessel density; retinal nerve fiber layer; choroidal microvascular dropout
• Online Access: http://ies.ijo.cn/cn_publish/2021/1/202101011.pdf

With the development of science and the progress of society,a revolutionary breakthrough-optical coherence tomography angiography(OCTA), a non-invasive imaging-assisted examination method-has been achieved, in the study of hemodynamics of the fundus of primary glaucoma in recent years. This technology has many advantages compared with previous traditional inspection methods. It fully exercises split-spectrum amplitude decorrelation angiography(SSADA)to acquire three-dimensional blood flow images of the fundus. With characteristics of none invasion but fastness, repeatability, layered imaging and high resolution, it can stratify and quantify the fundus blood flow density, and is also used to monitor the early changes of glaucoma fundus blood flow, disease progression and evaluation of therapeutic effect. However, OCTA presents certain shortcomings in actual clinical applications. Before available to function more widely in the fields of glaucoma disease, this method demands further researches and development. This article gives an overview of the application and research progress of OCTA technology in primary glaucoma.