Asbestos-Induced Cellular and Molecular Alteration of Immunocompetent Cells and Their Relationship with Chronic Inflammation and Carcinogenesis

Asbestos-Induced Cellular and Molecular Alteration of Immunocompetent Cells and Their Relationship with Chronic Inflammation and Carcinogenesis

Asbestos causes lung fibrosis known as asbestosis as well as cancers such as malignant mesothelioma and lung cancer. Asbestos is a mineral silicate containing iron, magnesium, and calcium with a core of SiO2. The immunological effect of silica, SiO2, involves the dysregulation of autoimmunity becaus...

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Main Authors: Hidenori Matsuzaki, Megumi Maeda, Suni Lee, Yasumitsu Nishimura, Naoko Kumagai-Takei, Hiroaki Hayashi, Shoko Yamamoto, Tamayo Hatayama, Yoko Kojima, Rika Tabata, Takumi Kishimoto, Junichi Hiratsuka, Takemi Otsuki
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/492608

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