Respiratory Syncytial Virus Infection Disrupts Monolayer Integrity and Function in Cystic Fibrosis Airway Cells

Respiratory Syncytial Virus Infection Disrupts Monolayer Integrity and Function in Cystic Fibrosis Airway Cells

Background: Respiratory Syncytial Virus (RSV) infection is a common contributor to pulmonary symptoms in children with cystic fibrosis (CF). Here we examined RSV infection in immortalized bronchial epithelial cells (CFBE41o-) expressing wild-type (wt) or F508del cystic fibrosis transmembrane conduct...

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Bibliographic Details
Main Authors: Wayne Sullender, John Paul Clancy, Rhonda Szczesniak, Eric Sorscher, Jeong Hong, Patrick Maeng, Michele Kong
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Viruses
Subjects:
Respiratory Syncytial Virus
bronchial epithelial cells
cystic fibrosis
F508del cystic fibrosis transmembrane conductance regulator (CFTR)
Online Access:http://www.mdpi.com/1999-4915/5/9/2260

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http://www.mdpi.com/1999-4915/5/9/2260

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