Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis
Abstract Background Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease, and gene expression profiling has identified several molecular subtypes with distinct biological and clinicopathological characteristics. While MIBC subtyping has primarily been based on messenger RNA (mRNA), long...
Main Authors: | Joep J. de Jong, Yang Liu, A. Gordon Robertson, Roland Seiler, Clarice S. Groeneveld, Michiel S. van der Heijden, Jonathan L. Wright, James Douglas, Marc Dall’Era, Simon J. Crabb, Bas W. G. van Rhijn, Kim E. M. van Kessel, Elai Davicioni, Mauro A. A. Castro, Yair Lotan, Ellen C. Zwarthoff, Peter C. Black, Joost L. Boormans, Ewan A. Gibb |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-10-01
|
Series: | Genome Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13073-019-0669-z |
Similar Items
-
Discovery of a genomic classifier for predicting clinically aggressive luminal bladder tumors with higher rates of pathological upstaging
by: J.J. De Jong, et al.
Published: (2020-07-01) -
Prospective bladder cancer infrastructure for experimental and observational research on bladder cancer: study protocol for the ‘trials within cohorts’ study ProBCI
by: Lambertus A Kiemeney, et al.
Published: (2021-06-01) -
A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable.
by: Kim E M van Kessel, et al.
Published: (2017-01-01) -
A showcase study on personalized in silico drug response prediction based on the genetic landscape of muscle invasive bladder cancer
by: Friedemann Krentel, et al.
Published: (2021-03-01) -
Targeted Therapy in Metastatic Bladder Cancer: Present Status and Future Directions
by: Mathijs Scholtes, et al.
Published: (2020-10-01)