High-Resolution Mapping of Genomic Imbalance and Identification of Gene Expression Profiles Associated with Differential Chemotherapy Response in Serous Epithelial Ovarian Cancer

High-Resolution Mapping of Genomic Imbalance and Identification of Gene Expression Profiles Associated with Differential Chemotherapy Response in Serous Epithelial Ovarian Cancer

Array comparative genomic hybridization (aCGH) and microarray expression profiling were used to subclassify DNA and RNA alterations associated with differential response to chemotherapy in ovarian cancer. Two to 4 Mb interval arrays were used to map genomic imbalances in 26 sporadic serous ovarian...

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Bibliographic Details
Main Authors: Marcus Bernardini, Chung-Hae Lee, Ben Beheshti, Mona Prasad, Monique Albert, Paula Marrano, Heather Begley, Patricia Shaw, Al Covens, Joan Murphy, Barry Rosen, Salomon Minkin, Jeremy A. Squire, Pascale F. Macgregor
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
cisplatin
taxol
gene amplification
gene deletion
microarray data mining
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800818

Internet

http://www.sciencedirect.com/science/article/pii/S1476558605800818

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